Genetic interaction between Inx2TA181 and sodium pump mutants - wing phenotypes.
Wing phenotypes arising from genetic interaction of Inx2TA181 and Na+/K+ ATPase α and β subunit mutants. The figure shows representative mutant wings of the indicated genotypes with the proviso that the phenotypes are quite variable. row 1, removal of a single copy of nrv2, via the nwu3 allele, produces wing serration, weak Delta-like phenotypes (extra bits of vein material) and loss of some cross-veins. A small portion of longitudinal vein LII is also faint. Flies grown at 18oC. row 2, wing shows loss of portions of longitudinal veins LII and LV (*) and wing serration at the posterior margin when a single copy of ATPα is removed (allele M1176). Flies grown at 18oC. row 3, when a single copy of the α and the β subunit of the Na+/K+ ATPase are simultaneously removed (via nrv2nwu3 and ATPαM1176) wings are often small, lack wing margin and longitudinal veins do not extend to the edge of the wing blade. These phenotypes are very similar to those seen in flies carrying the deficiency Df(3L)BSC7, row 4,, which removes nrv1 and nrv2 ...and many other genes. As mentioned, phenotypes for all genotypes are variable, ranging from weak to strong.