Innexin Gap Junctions

Image viewer

Inx2 and Ogre proteins co-localise in salivary gland cells.

Inx2 and Ogre proteins co-localise in salivary gland cells.

Innexin2 and myc-tagged Ogre colocalise in salivary gland cells. Shown above are two Z sections taken at different positions across the boundary of a pair of salivary gland cells. Inx2 (red, Alexa 555) and Ogre-myc (green, Alexa 488, myc-tagged Ogre) produce a yellow colour in the merged image at points where they overlap. Transgenically expressed Ogre-myc can accumulate within cells producing a weak green cytoplasmic background fluorescence. Size bar = 5μm. Inx2 and Inx3 are mutually dependent (Lehmann et al, 2006), so it is not surprising that endogenous Inx3 also co-localises with transgenic Ogre-myc in salivary gland cells. The potential interaction between Ogre and other innexins is not restricted to the salivary gland tissue: in brain neuropile glia, Inx2 colocalises with Ogre-myc.

Related Images:

Warning: Unknown: write failed: Disk quota exceeded (122) in Unknown on line 0

Warning: Unknown: Failed to write session data (files). Please verify that the current setting of session.save_path is correct (/tmp) in Unknown on line 0