Innexin Gap Junctions

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Adult wing expressing UAS-inx7.


Adult wing expressing UAS-inx7.

Photograph of an adult wing of genotype 2GM1GAL4 /+; UAS-inx73U7X8 /+. Expression of UAS-inx7 in intervein domains during wing development appears to result in more cells than normal adopting the vein cell-fate, leading to thicker wing veins (arrows) than those observed in wild type flies. It is possible that UAS-inx7 disrupts some of the paracrine signaling pathways ( Lechner et al. 2007), such as Notch, that are involved in establishing the vein/intervein boundaries, and consequently alters the distribution of cells adopting vein/intervein cell-fates.



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