Innexin Gap Junctions

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Actin distribution relative to plaques in the basal half of the pupal salivary gland cell.


Actin distribution relative to plaques in the basal half of the pupal salivary gland cell.

This series of images shows the intercellular boundary between two pupal salivary gland cells. The long lasting first image is an optical section at the basal end of the cell and subsequent images in the sequence are sections progressing in an apical direction up to the nucleus. The nucleus is located approximately half-way along the cells. Gap junction plaques are located mostly in the basal half of the cell. So, this image sequence ends in the apical-most region of the plaques and it reveals some small Inx2 (green) vesicles apparently engulfed by F-actin (red) fibres in this zone (..OK..you have to look real hard...they appear as yellow spots...). It is unknown whether new innexin subunits are incorporated into the cell membrane at the basal or apical end (...or both...) in the region occupied by gap junction plaques (See: Innexin lifecycle). A short summary of innexin and actin positional-associations can be found here.



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